Regulating the Drug Pushers

August 30, 2007

Quick, can you tell me what the side effects of Eli Lilly’s (NYSE: LLY) impotence drug Cialis are? Probably not, but I bet you know that it’ll make your spouse smile.

The FDA plans to run a study to see whether positive images and statements are causing viewers to ignore the warnings about potential side effects. It needs to run a study to figure this out? Of course happy families frolicking in the park are helping viewers to ignore the fast-talking guy at the end of the advertisement.

The announcement follows a New England Journal of Medicine study published last week, suggesting that FDA regulation of the advertisements is on the decline. According to the article, the number of regulatory actions dropped from 142 in 1997 to only 21 in 2006. While I guess it’s possible that the pharmaceutical industry is doing a better job at regulating itself, it seems more likely that the FDA is understaffed for the increasing number of direct-to-consumer (DTC) advertisements. Spending on DTC ads increased 330% from 1996 to 2005.

The FDA hasn’t been completely negligent when it comes to advertisements. Just this month, Pfizer (NYSE: PFE) received a warning letter from the FDA regarding a misleading advertisement in a professional journal. The agency took exception to the ad’s failure to include some of the side effects of its schizophrenia drug Geodon. The FDA was also none too pleased with Pfizer’s claims that Geodon has “proven advantages” over the intramuscular version of Johnson & Johnson (NYSE: JNJ) subsidiary Ortho-McNeil’s antipsychotic haldol — advantages the agency says weren’t proven in clinical trials.

Discount Pharmacy - Buy Pharmacy at discount prices including free shipping.Discount Pharmacy provides confortable and easy way to order discount pharmacy online.In the future, misleading ads might cost pharmaceutical companies more than just the expense of redoing the ads. The PDUFA reauthorization bill that comes out of Congress’ conference committee may give the FDA the ability to levy fines up to $250,000 for false or misleading advertisements.

In an effort to be proactive, the industry’s trade group — whose membership includes Merck (NYSE: MRK), Wyeth (NYSE: WYE), and Pfizer, as well as most other pharmaceutical companies — recently proposed that companies pay the FDA $80,000 to review each ad. House lawmakers rejected the idea, because having companies pay for the review would create a conflict of interest. Hello? What do they think the PDUFA is? Paying the government for oversight is pretty common in the U.S. The building permit fees I paid so that the inspector could check out my construction job haven’t seemed to put him on my side.

Changes to the oversight of advertisements are certainly something for investors to keep an eye on. Any increased regulation by the FDA will likely have a negative effect on drug companies. Sales of blockbuster-status drugs will be hurt most by restrictions placed on drug companies, but even the lowly oncology drugs, which get some advertisements in professional journals, might be affected.

Posted by toshko under Cialis News | Comments (0)

 Votes | Average: 0 out of 5 Votes | Average: 0 out of 5 Votes | Average: 0 out of 5 Votes | Average: 0 out of 5 Votes | Average: 0 out of 5 (No Ratings Yet)
Loading ... Loading ...

Go 2 Guy: Golf’s senior set an open bunch

August 26, 2007

SNOQUALMIE — OK, it’s not the PGA Tour, and it’s not the LPGA Tour, but here’s what I like about the Champions Tour — the players are personable, approachable and actually remember the ’70s.

They reigned in my day, and it’s good to see them again, old friends I’ve seen so many times on TV, live and at Snoqualmie Ridge, here for the third annual Boeing Classic.

When you reach 50, as I have, these are your peers, and it’s fun to reminisce. I recall many late nights watching them on my Sony Betamax and getting mad when the tape ran out before the tournament ended.

I’m a golf junkie, and it’s nice to hear that Dana Quigley is, too. When he’s not playing golf, he watches golf on the Golf Channel. It says in his bio that he has no hobbies besides golf, and he golfs every other day. How can you not root for a guy like that?

Quigley was never featured on those Betamax tapes because he didn’t start winning until he hit the oldster circuit, and I forgot to ask him why that was because I was busy asking him questions that had nothing to do with much of anything.

I thought about writing a hard-hitting column with reaction to Gary Player’s comments at the British Open concerning use of performance-enhancing drugs by pro golfers.

“Whether it’s HGH, whether it’s creatine or whether it’s steroids, I know for a fact that some golfers are doing it,” Player was quoted as saying.

But then I thought, wait a minute, I don’t care if they are or aren’t. (They’re not, according to the players I talked to, all four of them.)

Mark O’Meara’s not convinced that steroids would help a golfer, but you could argue that it would make the game more appealing with 55-year-olds hitting 400-yard drives.

Ed Dougherty said he was saddened by Player’s remarks, but if I had to guess, I’d say that someone partakes — if not on this tour, the other one. Just because no one knows of anyone doing it doesn’t mean that no one’s doing it. Athletes look for an edge, and if these guys were different, they’d still be using persimmon woods and 1-irons.

But on to other drug-related matters — the Champions Tour is reluctant to have alcoholic-beverage sponsors because of the message it might send to kids. But Cialis is a major sponsor, and Quigley wonders how a parent explains that one to his 10-year-old if she asks about the drug for erectile dysfunction.

Which led to the next obvious question: “If Cialis is a sponsor, do players get it free?”

“No,” Quigley said. “If we did, you’d see a lot more smiling faces out here.”

Quigley is smiling anyway. His Red Sox are in first place. He won a lousy $92,298 on the PGA Tour, and has won more than $13 million on the Champions Tour. If you have offbeat questions, fire away.

Internet Pharmacy - Buy Pharmacy at reasanoble prices.Internet Pharmacy provides confortable and easy way to order pharmacy via internet.The 60-year-old New England native was on the range, smoking a cigar, wearing chartreuse pants and a pained expression. He was jokingly complaining about the big picture The Seattle Times published of fellow competitor Jim Thorpe.

“That made me want to end my subscription, and I don’t even subscribe,” he said.

“But what if that picture had been of you?” I asked.

“Then it wouldn’t have been big enough,” he said.

I asked him how long it would take until the Mariners had a better record than the Red Sox.

“It won’t be anytime in our lives,” he said. “The Mariners? They play baseball?”

Quigley could name only two players on the local nine — Ichiro Suzuki and Felix Hernandez — and mocked the Joel Pineiro Era in Boston, which started last spring and ended this summer.

“I’m gonna put him in a category just above Eric Gagne,” Quigley said in reference to the struggling Red Sox reliever.

Quigley used to play drunk on the PGA Tour but said he never played hung over because he drank all night, so that wasn’t possible. He didn’t have a drink of choice.

“It wouldn’t matter,” he said. “I’d start with beer, drink wine with dinner, and depending on where I was, have real alcohol after that.

“I played a lot under the influence. I didn’t do it for my nerves. I did it because I couldn’t put the bottle down.”

Driving home loaded from his club on Feb. 1, 1990, he decided to quit because he was afraid he might kill someone. Quigley said he has not had a drink since but misses it every single day.

“The desire to drink doesn’t ever go away,” he said.

I asked what he thought about Michelle Wie, and he said she’s been poorly managed and that “playing with the guys was wrong.”

“What comes to mind when you think of Natalie Gulbis?” I asked.

“Hot,” he said. “H-O-T-T-T!”

He’s also a Tiger Woods fan, marveling at the man like everyone else. He once saw him hit a 30-yard pitch to a front pin and suck it back to the hole. In all his years, Quigley has never done that.

Best ever? “No question about it,” Quigley said. Better than Nicklaus? “Jack was a perfect golfer every time he played,” Quigley said. “Tiger still wins when he’s not playing well. That’s the sign of a great golfer.”

The golfers at Snoqualmie Ridge are not quite as great, but not nearly as private, and open for your viewing pleasure this weekend

Posted by toshko under Cialis News | Comments (0)

 Votes | Average: 0 out of 5 Votes | Average: 0 out of 5 Votes | Average: 0 out of 5 Votes | Average: 0 out of 5 Votes | Average: 0 out of 5 (No Ratings Yet)
Loading ... Loading ...

Sarkozy vows to get tough as paedophile crisis deepens

August 23, 2007

France faced up to its failure to handle sex criminals yesterday after fresh disclosures in a paedophile case prompted President Sarkozy to promise tough, British-style measures to keep lifelong tabs on offenders.

The case of Francis Evrard, 61, who was arrested last week after kidnapping a five-year-old boy, stirred outrage because of the circumstances of his release from prison last month after serving 18 years for child rape.

Among these were that Evrard was given Viagra, the anti-impotence drug, by two doctors shortly before he left the prison in the Normandy city of Caen. He had also collected paedophile pictures and talked to prison officers in crude language about his continuing attraction to children just before his release, Le Figaro reported.

President Sarkozy announced plans to bar the early release of prisoners and the creation of secure hospitals to retain, if necessary, offenders whose terms have ended. He called for voluntary “chemical castration” for released paedophiles and electronic monitoring of their movements. “Everything must be put in place to make sure this doesn’t happen again,” he said.

Pharmacy - Buy Pharmacy at discount prices including free shipping.Discount Pharmacy provides confortable and easy way to order discount pharmacy online. function pictureGalleryPopup(pubUrl,articleId) { var newWin = window.open(pubUrl+’template/2.0-0/element/pictureGalleryPopup.jsp?id=’+articleId+’&&offset=0&&sectionName=WorldEurope’,'mywindow’,'menubar=0,resizable=0,width=615,height=655′); }

Evrard was arrested two weeks after he failed to report for medical supervision. His case, and others, have shown the underfunded justice system’s inability to deal with sex criminals. Since his arrest, Evrard has told police that he had had relations with about 40 children although he had been convicted of molesting only three, Le Parisien newspaper said.

The doctors who prescribed the Viagra said that they had no access to the criminal backgrounds of the prisoners they treated.

Prison guards said that they were worried about the release next weekend of a child rapist with a similar background to that of Evrard. “He is boasting openly that he is going to start again. Everyone should be warned,” said the wardens’ union.

Posted by toshko under Cialis News | Comments (0)

 Votes | Average: 0 out of 5 Votes | Average: 0 out of 5 Votes | Average: 0 out of 5 Votes | Average: 0 out of 5 Votes | Average: 0 out of 5 (No Ratings Yet)
Loading ... Loading ...

News Bites: Food labels, elections and a bajillion ways to spell Viagra

August 18, 2007

Unidentified people gather in a secure area for the six trapped coal miners families Friday in Huntington.

Discount Pharmacy - Buy Pharmacy at discount prices including free shipping.Discount Pharmacy provides confortable and easy way to order discount pharmacy online.The search for six miners missing deep underground was abruptly halted after a second cave-in killed three rescue workers and injured at least six others who were trying to tunnel through rubble to reach them. (AP Photo/Rick Bowmer)Yeah, but you don’t know where it’s been. P-I reporter Andrew Schneider looks into the dubious science behind food labels. Sure, the law requires that food producers say where it comes from, but apparently, it doesn’t say they have to be right

Posted by toshko under Cialis News | Comments (0)

 Votes | Average: 0 out of 5 Votes | Average: 0 out of 5 Votes | Average: 0 out of 5 Votes | Average: 0 out of 5 Votes | Average: 0 out of 5 (No Ratings Yet)
Loading ... Loading ...

Bedtime supplements, ‘male enhancement’ and the cult of the phallus

August 10, 2007

In my secretive teenaged experience of pornography, it was the back-of-issue advertisements for strange products that really fevered my imagination.

With their promises to heighten pleasure and prolong sexual experiences, these small-print ads gave me enticing glimpses into an as yet foreign adulthood where, evidently, tablets for extended pleasure were desirous or (gasp!) necessary.

The bottles and packages (ordinarily for pills of powdered Spanish fly) were tantalizing too, being forever out of reach.

Mine was not such a liberal household that I would be encouraged to mail-order dubious products for even more dubious purposes.

What I didn’t know then was that these products claimed to be aphrodisiacs; and, as such, they were simply the most current manifestation of a globe-spanning tradition with ancient roots.

In fact, the magical properties of aphrodisiacs (named after a to-die-for belt worn by Aphrodite herself that possessed the ability to “beget love where none exists, kindle carnal desires where there is only weariness, provide physical enjoyment instead of boredom, and initiate erotic adventure where there is otherwise only a lack of fantasy,” according to Christian Ratsch’s guide, Plants of Love) have been eagerly sought or creatively imagined throughout history.

And whatever form they take — from dried sea horse, gecko, scorpion, dragonfly, hummingbird, beetle and fly to antelope horn, pulverized jade, quail egg, raw onion, garlic clove, wolf fat, squash seed and donkey testicle — aphrodisiacs have been prized exactly for their mysterious and miraculous ability to compensate for sagging desire, failed attraction, sour moods and the sluggish responses of aging flesh.

Though those porn-mag products have since become readily available to my adult grasp, the curious teenager’s passion for Spanish fly eventually faded to nothing. I’ve never ordered as much as a sample.

Until recently, that is.


Over the past two months, a flotilla of sex-specific aphrodisiac compounds has been coursing throughout my body.

Especially formulated for and, of course, marketed to a male population that’s apparently worried about its flaccid performances, these “intimacy enhancers” — composed of miniscule doses of chicken embryo extract, Korean red ginger root, tomato lycopene concentrate, pine bark, puncture vine, oat concentrate, huang-qi root, maca root, yohimbe bark, saw palmetto berry, desert-living cistanche stem, Indonesian tongkat ali, epimedium herb, aginine, sarsaparilla root extract, ginkgo biloba root, roseroot, wild yam, Chinese wolfberry, nitric oxide, Indian woodapple, tadalafil, guava, sildenafil citrate, Chinese dodder seed, and vardenafil hydrochloride —have passed through my digestive tract and into my bloodstream.

Other than the irresistible pull of novelty, why bother with them?

Because the messages from these supplements are increasingly hard to avoid, for one.

Daily spam (from senders named ‘V-I-A-G-R-A Works’ and ‘Super Charge Your Cock!’) reminds me to “Be a New Man” or obtain a “Dick Stiffy in a Jiffy.”

Meanwhile, television and print ads for Viagra, Enzyte and Cialis sell seductive half-minute stories of thriving marriages and an increased self-confidence that inspires envy from onlookers.

Another reason to delve into this world of questionable enhancements, not unrelated to the first: so that I will “suffer no more!”

That’s what the industry’s promotional material tells me, anyway.

And if I’m not suffering now, it’ll happen soon. For guys, I’m informed, it’s all bad news performance-wise.

“Fifty percent of men age 50 or older report at least occasional erection problems,” I read. From another source, worse news: “Most men over the age of 30 are probably starting to feel the debilitating effects of lower testosterone production, which often leads to a diminished sex drive with infrequent and weaker erections.”

Conspiring together, enticing ads and alarming stats induce me to fortify my ever-weakening manhood. That way I’ll be happier and more successful, right?

If the growing presence of all these virility enhancing products implies a crisis in Erectionville, it’s equally possible to think instead that since this new industry is dependent on men feeling non-virile and in need of enhancement; it doesn’t strictly remedy an actual physical problem so much as create the desire for on-call erections and perpetually turbo-charged virility.

Arguably, like the ‘age-defying complexes’ of the beauty industry, these products promote the necessity of supplements far more than they solve actual “debilitating effects.”

Instead of “Purchase our face cream and you’ll become youthful, beautiful, desired and successful,” the message for men is: “Buy this and you’ll remain a real man.”

If the number of products is an accurate indicator, men are buying that logic.

Without question, virility supplementation is a rapid-growth market. Over the past few years the “male-enhancement industry” (as it’s named by penisreview.com, a website devoted to rating products whose sole purpose is to increase potency) has moved from discreet back-of-issue ads to front-and-centre retail, right next to calcium pills, protein powders and vitamins.

And at a handful of health food stores, sex shops, websites and gym supplement outlets, shelves of products confirm how quickly I could empty my bank account on Testo Boost, Biovigora, Herbagra, Natural V, Mega-V, Super-L, Arginmax, Viramax, Vig-RX, Erexium, Formula 4SX for Men, Vigor-Force, Eroxil for Men, Zencore, Vazomyne, Maxoderm, Vigor-Max, Vitrix, Ultimate Libido, Conquest, Magna RX+, ExtendIT, AttraXium, Veramale, Ultimate Male Energy, Viagra, Cialis, Levitra, Enzyte, Rize2, Xyience, and Ogoplex.

Faced with such a bounty, it really is tempting to believe there’s an epidemic requiring a vast army of cures.

Erections-by-the-pill aren’t cheap, either. A single, locally purchased capsule of an “herbal Viagra” pill like Rize2 or Zencore, for instance, is $11.25 (tax included), and a 10-pack of Super-L goes for $47.69 (but each dose is 2 capsules).

Internet Pharmacy - Buy Pharmacy at reasanoble prices.Internet Pharmacy provides confortable and easy way to order pharmacy via internet.

Locally dispensed, a single tablet of pharmaceutical giant product like Levitra or Cialis costs $17.50 (tax included). Daily “natural male enhancement” supplements such as Enzyte cost upward of $30/month.)

The majority of these over-the-counter pills are “proprietary blends,” special laboratory-measured combinations of herbs, minerals and animal parts (hyped as “super potent ingredients”) that, their manufacturers assure us, “enhance your sex drive and desire,” “boost desire and performance,” and “enhance sensation and provide firmer feeling erections.”

Or, in the words of the enthusiastic operator selling me Enzyte: “After just three months, Sir, you’ll be experiencing the hardest, most satisfying erections you’ve ever had.”

In contrast, the prescription pill manufacturers narrow their claim: “Viagra improves a man’s response to sexual stimulus. Remember, Viagra is not an aphrodisiac. In order for Viagra to work, you need to be sexually stimulated.”

My last — but not least — reason for engaging on this thoroughly enhancing journey?

Simple jack-ass curiosity (with a healthy portion of vanity).

Most men will admit that there’s something profoundly appealing about becoming a talking and walking erection, especially when they can show it off.

Freud might view it as a form of arrested infancy, but guys do feel quite accomplished and, well, manly when they’re stiff.

That may be particularly true for gay culture, where priapic Tom of Finland drawings and well-endowed porn stars are less fantasy figures than impractical role models.

Besides, according to promotional material, these chemical compounds should be able to increase my stamina and desire and enhance my sex drive.

Skeptical, I was curious to know whether they could keep their promise. Importantly, too: would they actually make me feel differently or better about myself as a male?

And since I’m a man who is primarily a bottom, there was also the question of how complete the supposed enhancement would be. Despite the vagueness of claims like “boost desire and performance,” the ultimate aim of all these pills appears to be stiff and durable erections. Manliness, then, is reduced to one telltale icon: the thrusting phallus.

Surely male sexual desire, performance and drive have far greater complexity than a “Dick Stiffy in a Jiffy”?

As the occasional recipient of all-thrust-and-no-finesse, I know that without talent and empathy, there’s little difference between a jackhammering top and a jackhammer.

As my own guinea pig, I was enthusiastic but my method was hardly methodical. Limited time and budget clashed with the massive number of products on the market.

Along with my willing lab assistant Alexander, I tried male enhancement supplements and both herbal and pharmaceutical versions of the one dose = one erection pills.

Yes, they all worked. The herbal ones, varying in their effectiveness and duration (generally kicking in well after the recommended “take one hour before an intimate encounter”), were also fun because in addition to getting erections there was the welcome effect you’d expect a real cousin of Aphrodite’s belt to produce: that primal and predatory groin-level sense of sexual fulfillment being your core purpose.’


In The Disposable Rocket, John Updike, an elder spokesman for heterosexual masculinity, unapologetically relates his views on the experience of being male:

“Yet against the enduring female heroics of birth and nurture should be set the male’s superhuman frenzy to deliver his goods: he vaults walls, skips sleep, risks wallet, health and his political future all to ram home his seed into the gut of the chosen woman. The sense of the chase lives in him as the key to life.”

For better or worse, with guys sexuality tends to always lead back to the stiff phallus delivering his goods.

The magnetic allure of Levitra or Zencore to its majority market (rather than for the smallish percentile with an actual medical condition called erectile dysfunction) results no doubt from its appeal to this enduring if reductive “I can fuck therefore I am” idea of manliness.

Of course a pill-fuelled “Dick Stiffy in a Jiffy” does not a man make. Nor does its presence in the bloodstream produce an accomplished Don Juan. But it can conjure temporary self-esteem. And, plain and simple, it’s pleasurable dumb fun.

For men with erectile dysfunction, I’m sure Viagra and company are a godsend. Others, recreational users, might want to think about their true value.

As is the case with any product that promises a magical transformation, men might want to take advice that may be as old as aphrodisiacs themselves: “buyer beware” and “buyer be self-aware.”

Posted by toshko under Cialis News | Comments (0)

 Votes | Average: 0 out of 5 Votes | Average: 0 out of 5 Votes | Average: 0 out of 5 Votes | Average: 0 out of 5 Votes | Average: 0 out of 5 (No Ratings Yet)
Loading ... Loading ...

Next step: Create the demand

August 7, 2007

WITH vast and profitable markets up for grabs, drug companies are aggressively reaching beyond doctors and taking their marketing messages directly to consumers.

Some of their promotional strategies have become hard to miss. Nightly news broadcasts — a beloved habit for aging Americans — are brought to you by the makers of prescription medications for high cholesterol, arthritis, Alzheimer’s disease and erectile dysfunction; an Internet search for a specific symptom, or a visit to any popular health site, will bring up sponsored links and blinking ads for at least one prescription medication used to treat that symptom; fans of NASCAR see Viagra advertised every time No. 6 Mark Martin’s car rounds the track. And women paging through a magazine for tips on reducing clutter can scarcely avoid the faces and personal stories of actresses who are managing their depression, osteoporosis or hot flashes with a brand-name pill.

In 1997, the FDA loosened regulations governing the advertisement of prescription medications directly to consumers. The change set off explosive growth in marketing aimed at a general audience long on interest and — compared with physicians — short on professional skepticism. Today, drug makers spend roughly $5 billion a year to run advertising campaigns that use many of the same appeals that marketers use to sell breakfast cereal and toothpaste.

A study published in the Annals of Family Medicine’s January-February issue analyzed the messages of 38 advertisements then running during prime-time TV and found that 95% used emotional appeals to sell the medication, often framing prescription-drug use as a means to regain lost control over some aspect of life. None mentioned lifestyle change as an alternative to product use, although roughly 1 in 5 advertisements suggested it might be a useful complement to the drug. One in 4 described the causes of the disease the advertised drug treats, who is at risk for it or how frequently the condition occurs in the population. The study’s authors, led by UCLA researcher Dominick L. Frosh, suggested that without such information, consumers would have little reason to see prescription medication as a solution that involves risks as well as possible benefits.

In all, 58% portrayed the advertised drug as a medical breakthrough — a pharmaceutical twist on Madison Avenue’s “new and improved” message.

“It is time to ban direct-to-consumer advertising of prescription drugs,” wrote Dr. Kurt Stange, editor of the Annals, in an accompanying editorial. The advertisements consumers see “distort the relationship between patients and clinicians. [They] manipulate a patient’s agenda and steal precious time away from an evidence-based primary care clinician agenda that is attempting to promote healthy behavior, screen for early-stage treatable disease and address mental health.”

Even after 23 major pharmaceutical companies agreed to a new slate of voluntary guidelines limiting their advertising, Stange wasn’t buying it. Self-monitoring, he wrote, “is not working . . . and cannot realistically be expected to work.”

PhRMA, the drug manufacturers’ industry group, says direct-to-consumer advertising empowers patients to take an active role in their healthcare and spurs them to discuss symptoms, diseases and treatment options with their doctors that might otherwise go unraised. The industry group frequently cites a 2002 survey of consumers that found that 43% were spurred by a prescription-drug ad to look for more information about the drug or their health.

Although direct-to-consumer advertising has spurred the most political and professional debate, it is only the most visible means of prescription-drug marketing aimed at the consumer. To build markets and encourage consumer loyalty to their products, drug makers have invested heavily in a tactic known to public relations professionals as “third-party marketing.” Through voices, groups and activities that seem independent of them — but frequently are not — drug companies have found another way to get their messages to consumers.

‘Third-party’ approach

ACCORDING to an article published in the British Medical Journal in 2003, the top five public relations firms specializing in healthcare earned $300 million in 2002. These firms “are expert at ‘third-party technique’ — helping the drug industry separate the message from what could be seen as a self-interested messenger,” wrote authors Bob Burton and Andy Rowell.

Last October, a commentary in the New England Journal of Medicine detailed one little-noticed third-party marketing venture. Underwritten by Eli Lilly, the campaign was designed to increase the use in hospitals of a drug commercially known as Xigris, for the treatment of sepsis, or blood poisoning. A preliminary study had suggested some safety concerns with Xigris, and an FDA advisory panel had urged more thorough study of the drug before its approval. But in 2001, the FDA approved its entry into the market. The controversy appeared to sap first-year sales of Xigris, which fell short of Lilly’s expectations.

Lilly’s response was to secure the services of a small public relations firm, New York-based Belsito and Co. Belsito would begin spreading the word to physicians and media outlets specializing in medical news that Xigris was being rationed and that physicians were being “systematically forced,” because of the drug’s high cost, to decide which patients would live and which would die. A $1.8-million educational grant from Lilly would fund the creation of a group of physicians and bioethicists — named the “Values, Ethics and Rationing of Care Task Force” — to study this rationing and its ethical implications. And a Surviving Sepsis campaign was launched “in theory to raise awareness of severe sepsis and generate momentum toward the development of treatment guidelines,” wrote Dr. Peter Q. Eichacker and two fellow investigators based at the National Institutes of Health, in the NEJM.

Lilly’s financial inspiration of the campaign aimed at physicians, patients groups and the media was not apparent to many of the audiences reached. But its effect was quite clear, concluded a case study of the campaign done by the Council of Public Relations Firms: Sales of Xigris “have begun to trend upwards. Through the first quarter of 2004, Xigris sales were up 36%.”

In such campaigns, public relations companies operate as off-site extensions of a drug company’s marketing department. But sometimes, the relationship of a drug company and a third-party voice is more complex. The tie between patient-advocacy groups and drug companies is a good example.

Drug makers richly support the nation’s proliferating patient-advocacy groups, and only a handful of the charitable organizations refuse the sponsorship of pharmaceutical firms, says Georgetown University’s Dr. Adriane Fugh-Berman, who has studied these ties. That link presents rich marketing opportunities for corporate sponsors with an interest in reaching the patients the organizations advise and represent, Fugh-Berman says. But it also raises real questions about the independence of patients groups, she adds.

In marketing trade publications, the value of patients’ groups is widely touted. As friends and allies to potential customers, groups dedicated to patients who suffer from a specific condition can be powerful marketing tools. Patients seek information and emotional support from these groups, and trust them as an unbiased source of advice. Groups that empower patients to seek treatment are eager to foster awareness of their disease and, in the process, expand their membership. When they are successful, patients groups have a natural market-building effect.

Discount Pharmacy - Buy Pharmacy at discount prices including free shipping.Discount Pharmacy provides confortable and easy way to order discount pharmacy online.

Strength in numbers

WHEN insurers balk at reimbursing patients for new prescription medications, these groups typically swing into action, rallying sufferers to appear before public and consumer panels, contact lawmakers, and provide media outlets a human face to attach to a cause. Infertility patients mobilized by Resolve, for instance, have been extremely effective in extending states’ insurance coverage of infertility treatments. Groups such as the Depression and Bipolar Support Alliance have fielded experts and patients who have done the same for psychiatric conditions. And a wide range of patient groups, most with substantial backing from the makers of erectile dysfunction drugs, have mounted successful campaigns to get wary insurers to cover drugs such as Levitra, Viagra and Cialis.

Posted by toshko under Cialis News | Comments (0)

 Votes | Average: 0 out of 5 Votes | Average: 0 out of 5 Votes | Average: 0 out of 5 Votes | Average: 0 out of 5 Votes | Average: 0 out of 5 (No Ratings Yet)
Loading ... Loading ...

Cialis gaining on Viagra

August 2, 2007

When Eli Lilly and Co. thought about how to market its erectile-dysfunction drug in Italy, the answer seemed natural: hold a series of tango workshops to help couples revive their passions.

As a professional couple danced on stage, Lilly and its partners in medical associations provided counselors and medical experts to talk to consumers about sexual health problems.

How Cialis plays in Europe is important to Lilly, which recently won approval to market a one-a-day version of the erectile-dysfunction drug there. The company also hopes to get U.S. approval later this year.

ADVERTISEMENT
OAS_AD(’ArticleFlex_1′);

Neither Viagra nor Levitra is sold in once-daily doses, which could give Lilly an edge.

The once-a-day version will be marketed for men who anticipate having sex two or more times a week, without confining it to a limited time.

The current dosage of Cialis works for about 36 hours. Viagra and the other major erectile-dysfunction drug, Levitra, work for about four hours.

Cialis trails rival Viagra in the U.S., but it’s the leader in 22 nations, from France to Mexico, in the $3 billion worldwide market for erectile dysfunction.

The pills all work the same way, by blocking an enzyme in men’s bodies, allowing men to get and maintain an erection.

Doctors say they expect Cialis’ once-a-day version to catch on. ”The baby boomer population is growing. I think a certain patient group could benefit. They want to take it now and be ready whenever,“ said Dr. Ronald Suh, who works at Urology of Indiana.

Some analysts say the once-a-day version could increase Lilly sales, but only modestly. But it could provide a steadier revenue stream than the current dosage of Cialis, which men take sporadically.

Discount Pharmacy - Buy Pharmacy at discount prices including free shipping.Discount Pharmacy provides confortable and easy way to order discount pharmacy online.

‘’Giving consumers more options is a positive step, but I don’t think it’s going to be a game-changing development for Lilly or the erectile-dysfunction market, at least in the short run,“ said Jason Fox, a drug analyst at H&R Block in Detroit.

‘’It seems more like a life-cycle management thing than something that’s completely new,“ said Les Funtleyder, an analyst at Miller Tabak & Co. in New York.
The erectile-dysfunction market continues to grow steadily, in high single-digit percentages, as the baby boomers get older and turn to the medicine cabinet for help in the bedroom.

Cialis has continued to gain market share every quarter since it was launched in 2003, Lilly said. And any continued improvement in Cialis results probably will help the bottom line at Lilly, which bought full control of the drug from partner Icos Corp. for $2.3 billion.

Lilly predicts Cialis sales will top $1 billion this year, giving it blockbuster status.
The company said in December that Cialis would become No. 1 outside the U.S. this year, beating out Viagra.

Lilly didn’t make any such predictions in the U.S., where Viagra continues to dominate. Still, Cialis’ U.S. market share climbed from 14 percent in 2003 to 27 percent last year, while Viagra’s fell from 73 percent to 56 percent in the same time, according to IMS Health.

Posted by toshko under Cialis News | Comments (0)

 Votes | Average: 0 out of 5 Votes | Average: 0 out of 5 Votes | Average: 0 out of 5 Votes | Average: 0 out of 5 Votes | Average: 0 out of 5 (No Ratings Yet)
Loading ... Loading ...

Breast-Cancer Treatment Robs Wife Of Sexual Desire

July 29, 2007

But before you can improve sexual desire and response, you need to heal. Not every woman (or partner) attaches the same degree of importance to the breasts (and uterus). For some women, these body parts are synonymous with sexuality and femininity. For others, they’re relatively unrelated. There are women who immediately choose breast reconstruction, and those who prefer to go “au natural.” Some miss the breast or nipple sensation they once had; others don’t. Each person is different, so don’t make assumptions.

You say that Jeannette is an “attractive, very young” 47-year-old. In what way has her perception of her own attractiveness changed? Or maybe it hasn’t. Have you both talked about this issue? How has her cancer treatment affected you? It’s not as obvious as one might think. Does she feel self-conscious when you touch her near or over her scar? How do you feel touching her body now? Do you make love with the lights on? What’s her preference - and yours? Is she distracted by unpleasant thoughts that interfere with her pleasure and sexual responsiveness?

The construction of satisfying sexual functioning is complex. Discussion will not only heal, it will deepen intimacy. Sex involves sensory enjoyment, contact and connection, positive thoughts, feelings and pleasurable responses. It can be loving and erotic - physical and emotional. It affects individuals and the relationship. But just because you’ve shared momentous passion in the past, doesn’t mean you can have it whenever you choose. I know this is puzzling to many couples. Having a history of being “easily orgasmic” is a strength and a limitation. You think you have your sexual “formula” mastered, and then it stops working for some reason. It’s as elusive as a butterfly. No wonder we get so frustrated and impatient when our sexual response gets diverted or blocked. And the more frustrated we become, the less likely we are to be turned on.

But let’s be realistic - you’ve both gone through some hellish times in the last eight months.

Your wife has been propelled into surgical menopause overnight. Her estrogen and half of her testosterone has been shut down. She has less blood flowing to her genitals, more vaginal dryness, and less testosterone to fuel her sex drive. But this doesn’t spell the end of orgasms; it just means you have to be a little more creative and patient with yourselves.

I know it’s easier said than done, but forget the goal of achieving orgasms, and explore each other in new ways. Do whatever you need to do to bring play, fantasy and fun back into your relationship. Once you relax more and stress less, the orgasms will return when you least expect them.

Internet Pharmacy - Buy Pharmacy at reasanoble prices.Internet Pharmacy provides confortable and easy way to order pharmacy via internet.

And there’s no need to suffer with vaginal dryness. Because Jeanette no longer has ovaries, she isn’t producing estrogen, so her clitoris may be less engorged, and she may feel less genital sensitivity. There are non-hormonal oral medications that have been found to be helpful with desire in some women.

Studies have shown that the anti-depressant, Wellbutrin (bupropion hydrochloride) may have “a pro-sexual effect” by increasing sexual desire. There have also been reports of improved blood flow in some women who take the PDE-5 inhibitors (Viagra, Levitra or Cialis). But these medications must be prescribed by your physician.

There are also several intravaginal estrogen products to help with vaginal dryness and thinning. I suggest you and Jeannette make an appointment to discuss your concerns with her physician or oncologist to determine which options are appropriate.

There are also nonhormonal lubricants (such as astroglide), botanical oils (such as zestra) and over-the-counter vaginal moisturizers (like Replens, Lubrin and K-Y “liquibeads” ovule) available without prescription.

I will sometimes recommend that my patients use Vitamin E gel caps. I tell them to make a tiny hole in the capsule with a clean needle and place the entire capsule into the vagina. Remember that Vitamin E can stain your clothing. You can also put a little vitamin E on the penis and use this as part of your warm-up time together.

But when all has been said and done, the most important sexual organ is the brain.

What you tell yourself about what it takes to have “great sex” creates your reality and your enthusiasm. Nothing in life stays static. There are ebbs and flows in all sexual relationships. Instead of comparing yourselves to the way it used to be, enjoy your experiences today. Discover new sensitivities, focus on what feels good, take your time and, above all, be patient with yourselves.

Posted by toshko under Cialis News | Comments (0)

 Votes | Average: 0 out of 5 Votes | Average: 0 out of 5 Votes | Average: 0 out of 5 Votes | Average: 0 out of 5 Votes | Average: 0 out of 5 (No Ratings Yet)
Loading ... Loading ...

Premier: Food safety a top priority

July 26, 2007

Premier Wen Jiabao yesterday pledged to improve food safety and product quality.

“Food safety and product quality concerns people’s health, a producer’s credibility and a country’s image. Full attention must be paid on the issue,” Wen told a cabinet meeting.

He called for strengthened supervision on food and product quality throughout the whole production process and a strict tracking and recalling system of substandard goods.

Wen called on relevant departments to publicize food and product quality information to ensure the public is kept well informed.

The meeting agreed to set up a leading group on food safety made up of cabinet members.


In a related development, the Ministry of Agriculture announced yesterday to launch a nationwide inspection on forbidden chemicals and drugs used on farms.

Discount Pharmacy - Buy Pharmacy at discount prices including free shipping.Discount Pharmacy provides confortable and easy way to order discount pharmacy online.“It will mainly target the fishery and husbandry sectors to crack down on the illegal use of forbidden pesticides, animal drugs and chemicals,” Zhang Yuxiang, the ministry spokeswoman, told a news briefing.

The ministry will also adopt other measures to ensure food safety through establishing pollution-free production bases, checking chemical application on farms, and strengthening certification of quality agriculture products, Zhang said.

China has been confronted with food safety problems since last year, when mandarin fish from Guangdong Province and turbot from Shandong were found to contain malachite.

Zhang said the country had established a nationwide food product tracking system from the farmland to the dining table.

The country is also trying to set up a market entry scheme for food products in major cities such as Beijing, Shanghai and Dalian, before it expands to other cities in the future, Zhang said.

According to the latest report by the Japanese food watchdog, 99.42 percent of food imported from China was quality, an approval rate higher than those from the United State and European Union.

“Japan adopted the strictest fishery inspection rule last year, and the report shows that Chinese fishery products have passed the tests,” Chen Yide, vice-director of the fishery bureau of the ministry, said.

Posted by toshko under Cialis News | Comments (0)

 Votes | Average: 0 out of 5 Votes | Average: 0 out of 5 Votes | Average: 0 out of 5 Votes | Average: 0 out of 5 Votes | Average: 0 out of 5 (No Ratings Yet)
Loading ... Loading ...

China seizes Viagra in crackdown on fake drugs

July 26, 2007

Police in China seized one ton of fake Viagra pills during a series of raids on gangs that were making counterfeit drugs to sell domestically and overseas.

F

Aside from the the popular anti-impotency drug, fake versions of Tamiflu, which is being stockpiled around the world for a potential bird flu pandemic, and anti-malarial medications were uncovered, Xinhua news agency said Wednesday.

Discount Pharmacy - Buy Pharmacy at discount prices including free shipping.Discount Pharmacy provides confortable and easy way to order discount pharmacy online.Four gangs were busted making the drugs during a two-year crackdown that involved Chinese and US authorities, as well as Interpol, Xinhua said, citing the Ministry of Public Security.

The announcement of the busts come after the former head of China’s food and drug watchdog Zheng Xiaoyu was executed this month for taking bribes to approve medicines, some of which were unsafe.

The one ton of Viagra was uncovered in China’s southern Guangdong province that borders Hong Kong following a raid late last year made in co-operation with US law authorities, Xinhua said.

The Tamiflu raids in May also took place after acting on intelligence from US authorities, resulting in the arrests of 19 suspects. Xinhua said the gang had been trying to sell the Tamiflu into the United States via the Internet.

Few other details of the busts, or the expected trials of the suspects, were revealed.

Posted by toshko under Cialis News | Comments (0)

 Votes | Average: 0 out of 5 Votes | Average: 0 out of 5 Votes | Average: 0 out of 5 Votes | Average: 0 out of 5 Votes | Average: 0 out of 5 (No Ratings Yet)
Loading ... Loading ...

  Next Page »